Ranitidine prodn. by alkylating 2-thiomethyl-furan cpd

Prodn. of furan deriv. Q-SCH2CH2NHC(NHMe)=CHNO2 (I) comprises alkylating the thiol Q-SH (II) with R1R2N-C(-NHMe)=CHNO2 5-(dimethylaminomethyl)-2-furfuryl. R1 is CH2CH2L and R2 is H, or R1R2N is ethyleneimino. L is an eliminable gp. esp. halogen). Cpds. (II) and Q-SC(-NH2)=NH (IV) and their acid addn...

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Hauptverfasser:	BRADSHAW JOHN, CLITHEROW JOHN W
Format:	Patent
Sprache:	eng ; ita
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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