Notkun á mótlyfjum viðtaka GAL3 til þess að meðhöndla depru og/eða kvíða og efnasambönd sem eru nytsöm við aðferðirnar

This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This in...

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Hauptverfasser: JOHN M. WETZEL, HEIDI CHEN, HERMO JIMENZ, LAKMAN W. BOTEJU, IAN JAMIE TALISMAN, KITAE LIM, BHARAT LAGU, TOMAS P. BLACKBURN, MICHEAL KONKEL, STEWART NOBLE, MATHIVANAN PACKIARAJAN
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creator JOHN M. WETZEL
HEIDI CHEN
HERMO JIMENZ
LAKMAN W. BOTEJU
IAN JAMIE TALISMAN
KITAE LIM
BHARAT LAGU
TOMAS P. BLACKBURN
MICHEAL KONKEL
STEWART NOBLE
MATHIVANAN PACKIARAJAN
description This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. This invention also provides a method of treating depression and/or anxiety in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Notkun á mótlyfjum viðtaka GAL3 til þess að meðhöndla depru og/eða kvíða og efnasambönd sem eru nytsöm við aðferðirnar
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