"SUBSTITUTED CARBAMOYLEMETHYLAMINO ACETIC ACID DERIVATIVES AS NOVEL NEP INHIBITORS"

The present invention provides a compound of Formula (I); or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present...

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Bibliographische Detailangaben
Hauptverfasser: MOGI MUNETO, IWAKIYUKI, KSANDER GARY MICHAEL, KAWANAMI TOSHIO
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides a compound of Formula (I); or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.