"AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE AZILSARTAN"

"AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE AZILSARTAN"

The present invention relates to an improved process for the preparation of substantially pure compound of 2-Ethoxy-l-[[2'-(2,5-dihydro-5-oxo-l,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid (Azilsartan) of Formula I, with a reduced content of desethyl impurity less tha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KOTAGIRI VIJAYA KUMAR, YENUMULA RAGHAVENDRA RAO, BANDARI MOHAN, MURALIKRISHNA SURYADEVARA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to an improved process for the preparation of substantially pure compound of 2-Ethoxy-l-[[2'-(2,5-dihydro-5-oxo-l,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid (Azilsartan) of Formula I, with a reduced content of desethyl impurity less than 0.1% and an efficient, commercially viable process for the preparation of pure intermediates of Azilsartan.