FENOFIBRATE FORMULATION

Various fenofibrate dosage forms contain a plurality of beads or particles where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particle...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SHAW ANDREW ALAN, CHATTARAJ SARAT C, REDELMAN GLENN ALLEN
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator SHAW ANDREW ALAN
CHATTARAJ SARAT C
REDELMAN GLENN ALLEN
description Various fenofibrate dosage forms contain a plurality of beads or particles where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particles of a water soluble or water dispersible cellulosic binder. The mass ratio of the drug to the binder in the dosage form is between about 3.5:1 and 4.5:1; and the dosage form produces a first Cmax in vivo that is between about 10% and about 50% higher than a comparative Cmax produced by a comparative dosage form. The comparative dosage form comprises the drug and the binder in a ratio of between about 5:1 and 15:1.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_IN11040DELNP2014A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>IN11040DELNP2014A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_IN11040DELNP2014A3</originalsourceid><addsrcrecordid>eNrjZBB3c_Xzd_N0CnIMcVVw8w_yDfVxDPH09-NhYE1LzClO5YXS3Axqbq4hzh66qQX58anFBYnJqXmpJfGefoaGBiYGLq4-fgFGBoYmjsZEKwQAM1oiaQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>FENOFIBRATE FORMULATION</title><source>esp@cenet</source><creator>SHAW ANDREW ALAN ; CHATTARAJ SARAT C ; REDELMAN GLENN ALLEN</creator><creatorcontrib>SHAW ANDREW ALAN ; CHATTARAJ SARAT C ; REDELMAN GLENN ALLEN</creatorcontrib><description>Various fenofibrate dosage forms contain a plurality of beads or particles where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particles of a water soluble or water dispersible cellulosic binder. The mass ratio of the drug to the binder in the dosage form is between about 3.5:1 and 4.5:1; and the dosage form produces a first Cmax in vivo that is between about 10% and about 50% higher than a comparative Cmax produced by a comparative dosage form. The comparative dosage form comprises the drug and the binder in a ratio of between about 5:1 and 15:1.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150925&amp;DB=EPODOC&amp;CC=IN&amp;NR=11040DEN2014A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150925&amp;DB=EPODOC&amp;CC=IN&amp;NR=11040DEN2014A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHAW ANDREW ALAN</creatorcontrib><creatorcontrib>CHATTARAJ SARAT C</creatorcontrib><creatorcontrib>REDELMAN GLENN ALLEN</creatorcontrib><title>FENOFIBRATE FORMULATION</title><description>Various fenofibrate dosage forms contain a plurality of beads or particles where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particles of a water soluble or water dispersible cellulosic binder. The mass ratio of the drug to the binder in the dosage form is between about 3.5:1 and 4.5:1; and the dosage form produces a first Cmax in vivo that is between about 10% and about 50% higher than a comparative Cmax produced by a comparative dosage form. The comparative dosage form comprises the drug and the binder in a ratio of between about 5:1 and 15:1.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBB3c_Xzd_N0CnIMcVVw8w_yDfVxDPH09-NhYE1LzClO5YXS3Axqbq4hzh66qQX58anFBYnJqXmpJfGefoaGBiYGLq4-fgFGBoYmjsZEKwQAM1oiaQ</recordid><startdate>20150925</startdate><enddate>20150925</enddate><creator>SHAW ANDREW ALAN</creator><creator>CHATTARAJ SARAT C</creator><creator>REDELMAN GLENN ALLEN</creator><scope>EVB</scope></search><sort><creationdate>20150925</creationdate><title>FENOFIBRATE FORMULATION</title><author>SHAW ANDREW ALAN ; CHATTARAJ SARAT C ; REDELMAN GLENN ALLEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_IN11040DELNP2014A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SHAW ANDREW ALAN</creatorcontrib><creatorcontrib>CHATTARAJ SARAT C</creatorcontrib><creatorcontrib>REDELMAN GLENN ALLEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHAW ANDREW ALAN</au><au>CHATTARAJ SARAT C</au><au>REDELMAN GLENN ALLEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FENOFIBRATE FORMULATION</title><date>2015-09-25</date><risdate>2015</risdate><abstract>Various fenofibrate dosage forms contain a plurality of beads or particles where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particles of a water soluble or water dispersible cellulosic binder. The mass ratio of the drug to the binder in the dosage form is between about 3.5:1 and 4.5:1; and the dosage form produces a first Cmax in vivo that is between about 10% and about 50% higher than a comparative Cmax produced by a comparative dosage form. The comparative dosage form comprises the drug and the binder in a ratio of between about 5:1 and 15:1.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_IN11040DELNP2014A
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title FENOFIBRATE FORMULATION
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T00%3A27%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SHAW%20ANDREW%20ALAN&rft.date=2015-09-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EIN11040DELNP2014A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true