Nucleic acid containing nanoparticles

Herein disclosed are nanoparticles comprising a phospholipid, apolipoprotein and/or an apolipoprotein mimetic, sterol, cationic lipid or ionizable cationic lipid and a nucleic acid and compositions comprising such nanoparticles and a method for preparing such nanoparticles. The nanoparticles may be...

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Hauptverfasser: KLUZA Ewelina, HOFSTRAAT Stijn, ZWOLSMAN Robby Cornelis, ANBERGEN Tom, MULDER Willem J.M, FRANSEN Pieter Michele, VAN DER MEEL Roy, JANSSEN Henricus Marie
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creator KLUZA Ewelina
HOFSTRAAT Stijn
ZWOLSMAN Robby Cornelis
ANBERGEN Tom
MULDER Willem J.M
FRANSEN Pieter Michele
VAN DER MEEL Roy
JANSSEN Henricus Marie
description Herein disclosed are nanoparticles comprising a phospholipid, apolipoprotein and/or an apolipoprotein mimetic, sterol, cationic lipid or ionizable cationic lipid and a nucleic acid and compositions comprising such nanoparticles and a method for preparing such nanoparticles. The nanoparticles may be used as a medicament, such as in the treatment of a disease by stimulating or inhibiting an innate immune response.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Nucleic acid containing nanoparticles
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