Pharmaceutical salts of a chk-1 inhibitor

The invention provides a pharmaceutically acceptable salt of 5-[[5-[4-(4-fluoro-1-methyl-4-piperidyl)-2-methoxy-phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile which is selected from maleate, tosylate, besylate and malonate salts.Also provided are particular crystalline forms of the salts, met...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	PARKER Jake, MAJOR Meriel, NORTHEN Julian, TRAVERS Stuart
Format:	Patent
Sprache:	eng ; heb
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	PARKER Jake MAJOR Meriel NORTHEN Julian TRAVERS Stuart
description	The invention provides a pharmaceutically acceptable salt of 5-[[5-[4-(4-fluoro-1-methyl-4-piperidyl)-2-methoxy-phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile which is selected from maleate, tosylate, besylate and malonate salts.Also provided are particular crystalline forms of the salts, methods for the preparation of the salts, pharmaceutical compositions containing the salts and their therapeutic uses.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_IL308929A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>IL308929A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_IL308929A3</originalsourceid><addsrcrecordid>eNrjZNAMyEgsyk1MTi0tyUxOzFEoTswpKVbIT1NIVEjOyNY1VMjMy8hMyizJL-JhYE1LzClO5YXS3Axybq4hzh66qQX58anFBUAz8lJL4j19jA0sLI0sHY0JKgAA4PUm7A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Pharmaceutical salts of a chk-1 inhibitor</title><source>esp@cenet</source><creator>PARKER Jake ; MAJOR Meriel ; NORTHEN Julian ; TRAVERS Stuart</creator><creatorcontrib>PARKER Jake ; MAJOR Meriel ; NORTHEN Julian ; TRAVERS Stuart</creatorcontrib><description>The invention provides a pharmaceutically acceptable salt of 5-[[5-[4-(4-fluoro-1-methyl-4-piperidyl)-2-methoxy-phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile which is selected from maleate, tosylate, besylate and malonate salts.Also provided are particular crystalline forms of the salts, methods for the preparation of the salts, pharmaceutical compositions containing the salts and their therapeutic uses.</description><language>eng ; heb</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240101&DB=EPODOC&CC=IL&NR=308929A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240101&DB=EPODOC&CC=IL&NR=308929A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PARKER Jake</creatorcontrib><creatorcontrib>MAJOR Meriel</creatorcontrib><creatorcontrib>NORTHEN Julian</creatorcontrib><creatorcontrib>TRAVERS Stuart</creatorcontrib><title>Pharmaceutical salts of a chk-1 inhibitor</title><description>The invention provides a pharmaceutically acceptable salt of 5-[[5-[4-(4-fluoro-1-methyl-4-piperidyl)-2-methoxy-phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile which is selected from maleate, tosylate, besylate and malonate salts.Also provided are particular crystalline forms of the salts, methods for the preparation of the salts, pharmaceutical compositions containing the salts and their therapeutic uses.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAMyEgsyk1MTi0tyUxOzFEoTswpKVbIT1NIVEjOyNY1VMjMy8hMyizJL-JhYE1LzClO5YXS3Axybq4hzh66qQX58anFBUAz8lJL4j19jA0sLI0sHY0JKgAA4PUm7A</recordid><startdate>20240101</startdate><enddate>20240101</enddate><creator>PARKER Jake</creator><creator>MAJOR Meriel</creator><creator>NORTHEN Julian</creator><creator>TRAVERS Stuart</creator><scope>EVB</scope></search><sort><creationdate>20240101</creationdate><title>Pharmaceutical salts of a chk-1 inhibitor</title><author>PARKER Jake ; MAJOR Meriel ; NORTHEN Julian ; TRAVERS Stuart</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_IL308929A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; heb</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PARKER Jake</creatorcontrib><creatorcontrib>MAJOR Meriel</creatorcontrib><creatorcontrib>NORTHEN Julian</creatorcontrib><creatorcontrib>TRAVERS Stuart</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PARKER Jake</au><au>MAJOR Meriel</au><au>NORTHEN Julian</au><au>TRAVERS Stuart</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutical salts of a chk-1 inhibitor</title><date>2024-01-01</date><risdate>2024</risdate><abstract>The invention provides a pharmaceutically acceptable salt of 5-[[5-[4-(4-fluoro-1-methyl-4-piperidyl)-2-methoxy-phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile which is selected from maleate, tosylate, besylate and malonate salts.Also provided are particular crystalline forms of the salts, methods for the preparation of the salts, pharmaceutical compositions containing the salts and their therapeutic uses.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng ; heb
recordid	cdi_epo_espacenet_IL308929A
source	esp@cenet
subjects	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Pharmaceutical salts of a chk-1 inhibitor
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T09%3A08%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PARKER%20Jake&rft.date=2024-01-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EIL308929A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true