Aav virion encoding neurotrophic factor and uses thereof

Provided are recombinant adeno-associated virus (rAAV) virions, methods of treating an ocular condition, pharmaceutical compositions, and other compositions and methods, in which the rAAV virion comprises a poly nucleotide encoding a neurotrophic factor, such as Nerve Growth Factor (NGF) or Glial De...

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Hauptverfasser: NAU Jeffrey Alan, CARLSON Eric C
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creator NAU Jeffrey Alan
CARLSON Eric C
description Provided are recombinant adeno-associated virus (rAAV) virions, methods of treating an ocular condition, pharmaceutical compositions, and other compositions and methods, in which the rAAV virion comprises a poly nucleotide encoding a neurotrophic factor, such as Nerve Growth Factor (NGF) or Glial Derived Neurotrophic Factor (GDNF). Methods of treatment may include administration to the lacrimal gland.
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language eng ; heb
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Aav virion encoding neurotrophic factor and uses thereof
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