A dry powder inhaler and system for drug delivery

An inhalation system for delivering a dry powder medicament to a pulmonary tract, comprises a dry powder inhaler configured to have at least two inlet apertures, wherein a first inlet aperture is in communication with a first air flow pathway and a second inlet aperture is in communication with a se...

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Hauptverfasser: ANTHONY BRYANT, P. SPENCER KINSEY, JOHN M. POLIDORO, CARL R. SAHI, CHAD C. SMUTNEY, BENOIT ADAMO, TOM HE, SCOTT MCLEAN, ALFRED MANN, DENNIS OVERFIELD
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creator ANTHONY BRYANT
P. SPENCER KINSEY
JOHN M. POLIDORO
CARL R. SAHI
CHAD C. SMUTNEY
BENOIT ADAMO
TOM HE
SCOTT MCLEAN
ALFRED MANN
DENNIS OVERFIELD
description An inhalation system for delivering a dry powder medicament to a pulmonary tract, comprises a dry powder inhaler configured to have at least two inlet apertures, wherein a first inlet aperture is in communication with a first air flow pathway and a second inlet aperture is in communication with a second air flow pathway. The first airflow pathway and the second airflow pathway converge in a substantially perpendicular manner during an inhalation maneuver for deagglomerating powder particles. The inhalation system has a total resistance to flow in a dosing configuration ranging in value from 0.065 to about 0.200 (ˆškPa)/liter per minute. The inhaler may contain a cohesive powder e.g. a diketopiperazine, and the powder may contain insulin or another medicament.
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subjects DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title A dry powder inhaler and system for drug delivery
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