Carboxyesterase polypeptides for kinetic resolution

The present invention provides engineered carboxyesterase enzymes having improved properties as compared to a naturally occurring wild-type carboxyesterase enzymes, as well as polynucleotides encoding the engineered carboxyesterase enzymes, host cells capable of expressing the engineered carboxyeste...

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Bibliographische Detailangaben
Hauptverfasser: MAYO Melissa Ann, RIGGINS James Nicholas, HURTAK Jessica Anna, BERMUDEZ Ericka, SUBRAMANIAN Nandhitha, NOVICK Scott J, ENTWISTLE David, SOWELL-KANTZ Auric Anthony, VOLADRI Rama
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:The present invention provides engineered carboxyesterase enzymes having improved properties as compared to a naturally occurring wild-type carboxyesterase enzymes, as well as polynucleotides encoding the engineered carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes in hydrolysis reactions.