Methods and microorganisms for making 2,3-butanediol and derivatives thereof from c1 carbons
Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotro...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; heb |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | HELD Mark Anton TRINH Na CHAO Lily Yuin SCHAMLISCH Matthias Helmut HUYNH Tina YEH Bryan ZHAO Xinhua KEALEY James DIETZEL Kevin Lee |
| description | Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. These microorganisms and methods make use of molecular switches to regulate gene expression. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_IL268337B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>IL268337B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_IL268337B23</originalsourceid><addsrcrecordid>eNqFyrEKwjAQANAuDqJ-g_cBdrAB7awoCro5CuWaXNpgkyt3sd8viLvTW968eN4p9-wUMDmIwQqzdJiCRgXPAhFfIXVQbUzZvjMmcoGHb3YkYcIcJlLIPQmxBy8cwW7BorScdFnMPA5Kq5-LYn0-PY6XkkZuSEe0lCg311u1q43ZHyrzf3wAgcE6dA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Methods and microorganisms for making 2,3-butanediol and derivatives thereof from c1 carbons</title><source>esp@cenet</source><creator>HELD Mark Anton ; TRINH Na ; CHAO Lily Yuin ; SCHAMLISCH Matthias Helmut ; HUYNH Tina ; YEH Bryan ; ZHAO Xinhua ; KEALEY James ; DIETZEL Kevin Lee</creator><creatorcontrib>HELD Mark Anton ; TRINH Na ; CHAO Lily Yuin ; SCHAMLISCH Matthias Helmut ; HUYNH Tina ; YEH Bryan ; ZHAO Xinhua ; KEALEY James ; DIETZEL Kevin Lee</creatorcontrib><description>Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. These microorganisms and methods make use of molecular switches to regulate gene expression.</description><language>eng ; heb</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240901&DB=EPODOC&CC=IL&NR=268337B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240901&DB=EPODOC&CC=IL&NR=268337B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HELD Mark Anton</creatorcontrib><creatorcontrib>TRINH Na</creatorcontrib><creatorcontrib>CHAO Lily Yuin</creatorcontrib><creatorcontrib>SCHAMLISCH Matthias Helmut</creatorcontrib><creatorcontrib>HUYNH Tina</creatorcontrib><creatorcontrib>YEH Bryan</creatorcontrib><creatorcontrib>ZHAO Xinhua</creatorcontrib><creatorcontrib>KEALEY James</creatorcontrib><creatorcontrib>DIETZEL Kevin Lee</creatorcontrib><title>Methods and microorganisms for making 2,3-butanediol and derivatives thereof from c1 carbons</title><description>Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. These microorganisms and methods make use of molecular switches to regulate gene expression.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyrEKwjAQANAuDqJ-g_cBdrAB7awoCro5CuWaXNpgkyt3sd8viLvTW968eN4p9-wUMDmIwQqzdJiCRgXPAhFfIXVQbUzZvjMmcoGHb3YkYcIcJlLIPQmxBy8cwW7BorScdFnMPA5Kq5-LYn0-PY6XkkZuSEe0lCg311u1q43ZHyrzf3wAgcE6dA</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>HELD Mark Anton</creator><creator>TRINH Na</creator><creator>CHAO Lily Yuin</creator><creator>SCHAMLISCH Matthias Helmut</creator><creator>HUYNH Tina</creator><creator>YEH Bryan</creator><creator>ZHAO Xinhua</creator><creator>KEALEY James</creator><creator>DIETZEL Kevin Lee</creator><scope>EVB</scope></search><sort><creationdate>20240901</creationdate><title>Methods and microorganisms for making 2,3-butanediol and derivatives thereof from c1 carbons</title><author>HELD Mark Anton ; TRINH Na ; CHAO Lily Yuin ; SCHAMLISCH Matthias Helmut ; HUYNH Tina ; YEH Bryan ; ZHAO Xinhua ; KEALEY James ; DIETZEL Kevin Lee</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_IL268337B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; heb</language><creationdate>2024</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>HELD Mark Anton</creatorcontrib><creatorcontrib>TRINH Na</creatorcontrib><creatorcontrib>CHAO Lily Yuin</creatorcontrib><creatorcontrib>SCHAMLISCH Matthias Helmut</creatorcontrib><creatorcontrib>HUYNH Tina</creatorcontrib><creatorcontrib>YEH Bryan</creatorcontrib><creatorcontrib>ZHAO Xinhua</creatorcontrib><creatorcontrib>KEALEY James</creatorcontrib><creatorcontrib>DIETZEL Kevin Lee</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HELD Mark Anton</au><au>TRINH Na</au><au>CHAO Lily Yuin</au><au>SCHAMLISCH Matthias Helmut</au><au>HUYNH Tina</au><au>YEH Bryan</au><au>ZHAO Xinhua</au><au>KEALEY James</au><au>DIETZEL Kevin Lee</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Methods and microorganisms for making 2,3-butanediol and derivatives thereof from c1 carbons</title><date>2024-09-01</date><risdate>2024</risdate><abstract>Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. These microorganisms and methods make use of molecular switches to regulate gene expression.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; heb |
| recordid | cdi_epo_espacenet_IL268337B2 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Methods and microorganisms for making 2,3-butanediol and derivatives thereof from c1 carbons |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T14%3A12%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HELD%20Mark%20Anton&rft.date=2024-09-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EIL268337B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |