Tricyclic sulfones as rorgamma modulators

or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell...

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Bibliographische Detailangaben
Hauptverfasser: SHI Qing, CHERNEY Robert J, SRIVASTAVA Anurag S, BEAUDOIN BERTRAND Myra, DUAN Jingwu, CORNELIUS Lyndon A.M, MARCOUX David, BATT Douglas G, LIU Qingjie, DHAR T.G. Murali, WEIGELT Carolyn A
Format: Patent
Sprache:eng ; heb
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Zusammenfassung:or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.