Thiadiazinones

Thiadiazinones of the formula I wherein A is -CHR4-CHR5-, -CH2-CR4R5-, -CR4R5-CH2-, -CHR4-CHR5-CH2-, -CHR4-CH2-CHR5-, -CH2-CHR4-CHR5-, -CR4R5-CH2CH2-, -CH2-CR4R5-CH2- or -CH2CH2-CR4R5-, R1, R2, R3, R4 and R5 are each independently H, C1-5-alkyl, C2-5-alkenyl or C2-5-alkinyl, R3 is also C1-15-acyl, R...

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Hauptverfasser: JONAS ROCHUS DR, SCHLIEP HANS-JOCHEN, KLOCKOW MICHAEL DR, PIULATS JAIME DR, LUES INGEBORG DR
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creator JONAS ROCHUS DR
SCHLIEP HANS-JOCHEN
KLOCKOW MICHAEL DR
PIULATS JAIME DR
LUES INGEBORG DR
description Thiadiazinones of the formula I wherein A is -CHR4-CHR5-, -CH2-CR4R5-, -CR4R5-CH2-, -CHR4-CHR5-CH2-, -CHR4-CH2-CHR5-, -CH2-CHR4-CHR5-, -CR4R5-CH2CH2-, -CH2-CR4R5-CH2- or -CH2CH2-CR4R5-, R1, R2, R3, R4 and R5 are each independently H, C1-5-alkyl, C2-5-alkenyl or C2-5-alkinyl, R3 is also C1-15-acyl, R6 is H, alkyl, alkoxyl, OH, F, Cl, Br or I and Z is (H, H), (H, alkyl), (alkyl, alkyl) or O, the alkyl, alkenyl, alkinyl and/or alkoxy groups in each case containing up to 5 C atoms, but wherein, if A is -CH2CH2- and Z is O, one of the radicals R1, R2, R3 and R6 must be other than H, and salts thereof demonstrate positive inotropic action and are suitable for combating cardiovascular diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Thiadiazinones
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