ANTIVIRAL NUCLEOSIDE ANALOGUES

Antiviral nucleoside analogues contain a substituted benzimidazole base attached to a carbocyclic ring in place of the conventional sugar residue. Particularly preferred compounds include those in which the 2-, 5- and 6- positions of the benzimidazole base are substituted by halogen. The compounds h...

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Hauptverfasser: MARTIN,MICHAEL TOLAR, DRACH,JOHN CHARLES, TOWNSEND,LEROY B, GOOD,STEVEN SPENCER, DALUGE,SUSAN MARY
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creator MARTIN,MICHAEL TOLAR
DRACH,JOHN CHARLES
TOWNSEND,LEROY B
GOOD,STEVEN SPENCER
DALUGE,SUSAN MARY
description Antiviral nucleoside analogues contain a substituted benzimidazole base attached to a carbocyclic ring in place of the conventional sugar residue. Particularly preferred compounds include those in which the 2-, 5- and 6- positions of the benzimidazole base are substituted by halogen. The compounds have activity against herpes virus especially cytomegalovirus and also hepatitis B virus infections.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTIVIRAL NUCLEOSIDE ANALOGUES
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