PROCESS FOR PREPARING 1-[/2S/-METHYL-3-MERCAPTO-PROPIONYL]-PYRROLIDINE-/2S/-CARBOXYLIC ACID

The invention relates to a novel process for preparing 1-(/2S/-methyl-3-mercaptopropionyl)-pyrrolidine-/2S/-carboxylic acid of the formula I (* CHEMICAL STRUCTURE *) (I) in which 1-(/2S/-methyl-3-thiocyanatopropionyl)-pyrrolidine-/2S/-carboxylic acid of the formula II (* CHEMICAL STRUCTURE *) (II) i...

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Hauptverfasser: JAKFALVI,ELEMER, UERMOES,LASZLONE, DIETZ,ANDRAS, DINNYES,ISTVANNE, SCHNEIDER,GEZA, BLASKO,GABOR, KOVACS,JOZSEFNE, BECK,IVAN
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creator JAKFALVI,ELEMER
UERMOES,LASZLONE
DIETZ,ANDRAS
DINNYES,ISTVANNE
SCHNEIDER,GEZA
BLASKO,GABOR
KOVACS,JOZSEFNE
BECK,IVAN
description The invention relates to a novel process for preparing 1-(/2S/-methyl-3-mercaptopropionyl)-pyrrolidine-/2S/-carboxylic acid of the formula I (* CHEMICAL STRUCTURE *) (I) in which 1-(/2S/-methyl-3-thiocyanatopropionyl)-pyrrolidine-/2S/-carboxylic acid of the formula II (* CHEMICAL STRUCTURE *) (II) is dissolved in an aqueous mineral acid, the solution obtained is diluted with water and the 1-(/2S/-methyl-3-carbamoylthiopropionyl)-pyrrolidine-/2S/-carboxylic acid of the formula III (* CHEMICAL STRUCTURE *) (III) that forms is hydrolized with an aqueous solution of a base.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESS FOR PREPARING 1-[/2S/-METHYL-3-MERCAPTO-PROPIONYL]-PYRROLIDINE-/2S/-CARBOXYLIC ACID
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