PROCESS FOR PREPARING NOVEL BENZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AS ACTIVE SUBSTANCE
There are disclosed compounds having the formula wherein X is CR or N when n=1; or X is O, S, NR or CR when n=0; R is hydrogen or lower alkyl; Y is -CH2-, -S-, -O- or and A is Z is CH or N; R1 is halo or trifluoromethyl; R2 is hydrogen or halo; R3 is hydrogen or halo; with the proviso that when A is...
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| creator | BICKSLER,JAMES J,US KEES,KENNETH L,US PATTISON,THOMAS W,US MUSSER,JOHN H,US KREFT,ANTHONY F,US |
| description | There are disclosed compounds having the formula wherein X is CR or N when n=1; or X is O, S, NR or CR when n=0; R is hydrogen or lower alkyl; Y is -CH2-, -S-, -O- or and A is Z is CH or N; R1 is halo or trifluoromethyl; R2 is hydrogen or halo; R3 is hydrogen or halo; with the proviso that when A is naphthyl, Y is -O- and n=0, X is other than S; and their use in the treatment of inflammatory conditions and in the treatment of leukotriene-medicated naso-bronchial obstructive passageway conditions. |
| format | Patent |
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MUSSER,JOHN H,US ; KREFT,ANTHONY F,US</creatorcontrib><description>There are disclosed compounds having the formula wherein X is CR or N when n=1; or X is O, S, NR or CR when n=0; R is hydrogen or lower alkyl; Y is -CH2-, -S-, -O- or and A is Z is CH or N; R1 is halo or trifluoromethyl; R2 is hydrogen or halo; R3 is hydrogen or halo; with the proviso that when A is naphthyl, Y is -O- and n=0, X is other than S; and their use in the treatment of inflammatory conditions and in the treatment of leukotriene-medicated naso-bronchial obstructive passageway conditions.</description><edition>4</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1987</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19870728&DB=EPODOC&CC=HU&NR=T42447A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19870728&DB=EPODOC&CC=HU&NR=T42447A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BICKSLER,JAMES J,US</creatorcontrib><creatorcontrib>KEES,KENNETH L,US</creatorcontrib><creatorcontrib>PATTISON,THOMAS W,US</creatorcontrib><creatorcontrib>MUSSER,JOHN H,US</creatorcontrib><creatorcontrib>KREFT,ANTHONY F,US</creatorcontrib><title>PROCESS FOR PREPARING NOVEL BENZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AS ACTIVE SUBSTANCE</title><description>There are disclosed compounds having the formula wherein X is CR or N when n=1; or X is O, S, NR or CR when n=0; R is hydrogen or lower alkyl; Y is -CH2-, -S-, -O- or and A is Z is CH or N; R1 is halo or trifluoromethyl; R2 is hydrogen or halo; R3 is hydrogen or halo; with the proviso that when A is naphthyl, Y is -O- and n=0, X is other than S; and their use in the treatment of inflammatory conditions and in the treatment of leukotriene-medicated naso-bronchial obstructive passageway conditions.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1987</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjDEKwkAQRdNYiHoFmQvYaMB6Mpm4C8nOsrNJYROCrJVoIOL5NWJv9Xnw3l9mLx-EWBUqCeADewzWncBJxzUU7M5SQ8nBdhhtxwroSvAGQ4PEbbSENZA0XtRGK06_EKzOH9EwKDYM-MlozkHbQiM64nW2uA63KW1-u8q2FUcyuzQ--jSNwyXd07M3bcz3eX7Ew1_hDSNbOPo</recordid><startdate>19870728</startdate><enddate>19870728</enddate><creator>BICKSLER,JAMES J,US</creator><creator>KEES,KENNETH L,US</creator><creator>PATTISON,THOMAS W,US</creator><creator>MUSSER,JOHN H,US</creator><creator>KREFT,ANTHONY F,US</creator><scope>EVB</scope></search><sort><creationdate>19870728</creationdate><title>PROCESS FOR PREPARING NOVEL BENZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AS ACTIVE SUBSTANCE</title><author>BICKSLER,JAMES J,US ; KEES,KENNETH L,US ; PATTISON,THOMAS W,US ; MUSSER,JOHN H,US ; KREFT,ANTHONY F,US</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HUT42447A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1987</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>BICKSLER,JAMES J,US</creatorcontrib><creatorcontrib>KEES,KENNETH L,US</creatorcontrib><creatorcontrib>PATTISON,THOMAS W,US</creatorcontrib><creatorcontrib>MUSSER,JOHN H,US</creatorcontrib><creatorcontrib>KREFT,ANTHONY F,US</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BICKSLER,JAMES J,US</au><au>KEES,KENNETH L,US</au><au>PATTISON,THOMAS W,US</au><au>MUSSER,JOHN H,US</au><au>KREFT,ANTHONY F,US</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING NOVEL BENZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AS ACTIVE SUBSTANCE</title><date>1987-07-28</date><risdate>1987</risdate><abstract>There are disclosed compounds having the formula wherein X is CR or N when n=1; or X is O, S, NR or CR when n=0; R is hydrogen or lower alkyl; Y is -CH2-, -S-, -O- or and A is Z is CH or N; R1 is halo or trifluoromethyl; R2 is hydrogen or halo; R3 is hydrogen or halo; with the proviso that when A is naphthyl, Y is -O- and n=0, X is other than S; and their use in the treatment of inflammatory conditions and in the treatment of leukotriene-medicated naso-bronchial obstructive passageway conditions.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | PROCESS FOR PREPARING NOVEL BENZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AS ACTIVE SUBSTANCE |
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