PROCESS FOR PRODUCING THIAZOLIDINE-CARBOXYLIC ACID
The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl o...
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| creator | KRUSPERNE HAM,JUDIT,HU HORVATH,GEZA,HU BALINT,JANOS,HU GYOERGYDEAK,ZOLTAN,HU MILLE,TEREZIA,HU MIHOKNE BORBELY,ILDIKO,HU BOGNAR,REZSOE,HU SZENDE,BELA,HU HUSZKA,MARIANN,HU PUSZTAI,FERENC,HU JAKAB,ATTILA,HU JENEI,ANDRAS,HU KOVACS,ISTVAN,HU JANCSO,SANDOR,HU LAPIS,KAROLY,HU |
| description | The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin. |
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Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</description><edition>4</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1987</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19870528&DB=EPODOC&CC=HU&NR=T41774A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19870528&DB=EPODOC&CC=HU&NR=T41774A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KRUSPERNE HAM,JUDIT,HU</creatorcontrib><creatorcontrib>HORVATH,GEZA,HU</creatorcontrib><creatorcontrib>BALINT,JANOS,HU</creatorcontrib><creatorcontrib>GYOERGYDEAK,ZOLTAN,HU</creatorcontrib><creatorcontrib>MILLE,TEREZIA,HU</creatorcontrib><creatorcontrib>MIHOKNE BORBELY,ILDIKO,HU</creatorcontrib><creatorcontrib>BOGNAR,REZSOE,HU</creatorcontrib><creatorcontrib>SZENDE,BELA,HU</creatorcontrib><creatorcontrib>HUSZKA,MARIANN,HU</creatorcontrib><creatorcontrib>PUSZTAI,FERENC,HU</creatorcontrib><creatorcontrib>JAKAB,ATTILA,HU</creatorcontrib><creatorcontrib>JENEI,ANDRAS,HU</creatorcontrib><creatorcontrib>KOVACS,ISTVAN,HU</creatorcontrib><creatorcontrib>JANCSO,SANDOR,HU</creatorcontrib><creatorcontrib>LAPIS,KAROLY,HU</creatorcontrib><title>PROCESS FOR PRODUCING THIAZOLIDINE-CARBOXYLIC ACID</title><description>The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1987</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAKCPJ3dg0OVnDzD1IAsl1CnT393BVCPDwdo_x9PF08_Vx1nR2DnPwjIn08nRUcnT1deBhY0xJzilN5oTQ3g5yba4izh25qQX58anFBYnJqXmpJvEdoiImhubmJozFBBQC6uyYk</recordid><startdate>19870528</startdate><enddate>19870528</enddate><creator>KRUSPERNE HAM,JUDIT,HU</creator><creator>HORVATH,GEZA,HU</creator><creator>BALINT,JANOS,HU</creator><creator>GYOERGYDEAK,ZOLTAN,HU</creator><creator>MILLE,TEREZIA,HU</creator><creator>MIHOKNE BORBELY,ILDIKO,HU</creator><creator>BOGNAR,REZSOE,HU</creator><creator>SZENDE,BELA,HU</creator><creator>HUSZKA,MARIANN,HU</creator><creator>PUSZTAI,FERENC,HU</creator><creator>JAKAB,ATTILA,HU</creator><creator>JENEI,ANDRAS,HU</creator><creator>KOVACS,ISTVAN,HU</creator><creator>JANCSO,SANDOR,HU</creator><creator>LAPIS,KAROLY,HU</creator><scope>EVB</scope></search><sort><creationdate>19870528</creationdate><title>PROCESS FOR PRODUCING THIAZOLIDINE-CARBOXYLIC ACID</title><author>KRUSPERNE HAM,JUDIT,HU ; HORVATH,GEZA,HU ; BALINT,JANOS,HU ; GYOERGYDEAK,ZOLTAN,HU ; MILLE,TEREZIA,HU ; MIHOKNE BORBELY,ILDIKO,HU ; BOGNAR,REZSOE,HU ; SZENDE,BELA,HU ; HUSZKA,MARIANN,HU ; PUSZTAI,FERENC,HU ; JAKAB,ATTILA,HU ; JENEI,ANDRAS,HU ; KOVACS,ISTVAN,HU ; JANCSO,SANDOR,HU ; LAPIS,KAROLY,HU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HUT41774A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1987</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KRUSPERNE HAM,JUDIT,HU</creatorcontrib><creatorcontrib>HORVATH,GEZA,HU</creatorcontrib><creatorcontrib>BALINT,JANOS,HU</creatorcontrib><creatorcontrib>GYOERGYDEAK,ZOLTAN,HU</creatorcontrib><creatorcontrib>MILLE,TEREZIA,HU</creatorcontrib><creatorcontrib>MIHOKNE BORBELY,ILDIKO,HU</creatorcontrib><creatorcontrib>BOGNAR,REZSOE,HU</creatorcontrib><creatorcontrib>SZENDE,BELA,HU</creatorcontrib><creatorcontrib>HUSZKA,MARIANN,HU</creatorcontrib><creatorcontrib>PUSZTAI,FERENC,HU</creatorcontrib><creatorcontrib>JAKAB,ATTILA,HU</creatorcontrib><creatorcontrib>JENEI,ANDRAS,HU</creatorcontrib><creatorcontrib>KOVACS,ISTVAN,HU</creatorcontrib><creatorcontrib>JANCSO,SANDOR,HU</creatorcontrib><creatorcontrib>LAPIS,KAROLY,HU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KRUSPERNE HAM,JUDIT,HU</au><au>HORVATH,GEZA,HU</au><au>BALINT,JANOS,HU</au><au>GYOERGYDEAK,ZOLTAN,HU</au><au>MILLE,TEREZIA,HU</au><au>MIHOKNE BORBELY,ILDIKO,HU</au><au>BOGNAR,REZSOE,HU</au><au>SZENDE,BELA,HU</au><au>HUSZKA,MARIANN,HU</au><au>PUSZTAI,FERENC,HU</au><au>JAKAB,ATTILA,HU</au><au>JENEI,ANDRAS,HU</au><au>KOVACS,ISTVAN,HU</au><au>JANCSO,SANDOR,HU</au><au>LAPIS,KAROLY,HU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PRODUCING THIAZOLIDINE-CARBOXYLIC ACID</title><date>1987-05-28</date><risdate>1987</risdate><abstract>The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR PRODUCING THIAZOLIDINE-CARBOXYLIC ACID |
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