BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES

The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprisi...

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Bibliographische Detailangaben
Hauptverfasser:	BACAC, Marina, AST, Oliver, MOLHOJ, Michael, UMANA, Pablo, IMHOF-JUNG, Sabine, KLEIN, Christian, KLOSTERMANN, Stefan, REGULA, Joerg Thomas, SCHAEFER, Wolfgang, NEUMANN (formally JAEGER), Christiane
Format:	Patent
Sprache:	eng ; hun
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.