COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY

Compositions, methods, and systems are provided for pulmonary delivery of active agents via a metered dose inhaler. In some embodiments, the compositions comprise an HFO-1234ze(E) suspension medium, active agent particles, and suspending particles. The active agent particles may comprise one, two, t...

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Hauptverfasser: LAMPA, Charina, RIEBE, Michael, JOSHI, Vidya, GUTIERREZ, Gertrude, MELLO, Lauren, LECHUGA-BALLESTEROS, David, ARCHBELL, James, TAN, Penny, LACHACZ, Kellisa
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creator LAMPA, Charina
RIEBE, Michael
JOSHI, Vidya
GUTIERREZ, Gertrude
MELLO, Lauren
LECHUGA-BALLESTEROS, David
ARCHBELL, James
TAN, Penny
LACHACZ, Kellisa
description Compositions, methods, and systems are provided for pulmonary delivery of active agents via a metered dose inhaler. In some embodiments, the compositions comprise an HFO-1234ze(E) suspension medium, active agent particles, and suspending particles. The active agent particles may comprise one, two, three or four active agent(s) selected from a long-acting muscarinic antagonist (LAMA), a long-acting β2-agonists (LABA), a short-acting beta-agonists (SABA), an inhaled corticosteroid (ICS), and a non-corticosteroid anti-inflammatory agent.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY
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