MONOCLONAL ANTIBODY ANTAGONIZING AND INHIBITING BINDING BETWEEN HUMAN PD-1 ANTIGEN AND LIGAND THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Disclosed in the present invention is a monoclonal antibody or a derivative thereof which can antagonize and inhibit the binding of human PD-1 antigen to its ligand: the amino acid sequences of CDR1, CDR 2 and CDR 3 in the light chain variable region of the antibody are shown in SEQ ID NO:3, SEQ ID...

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Bibliographische Detailangaben
Hauptverfasser:	HU, Hongqun, ZHOU, Qunmin, CHEN, Zui, XU, Yiqing, CAI, Mingwen, LUO, Shiping, FAN, Jinling, SONG, Xiaoqi
Format:	Patent
Sprache:	eng ; hun
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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