BCMA (CD269/TNFRSF17) - BINDING PROTEINS

The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening a...

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Hauptverfasser: PARMAR, Radha Shah, CLEGG, Stephanie Jane, WATTAM, Trevor Anthony Kenneth, LEWIS, Alan Peter, CRAIGEN, Jennifer L, HAMBLIN, Paul Andrew, ALGATE, Paul, MAYES, Patrick
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creator PARMAR, Radha Shah
CLEGG, Stephanie Jane
WATTAM, Trevor Anthony Kenneth
LEWIS, Alan Peter
CRAIGEN, Jennifer L
HAMBLIN, Paul Andrew
ALGATE, Paul
MAYES, Patrick
description The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title BCMA (CD269/TNFRSF17) - BINDING PROTEINS
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