2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDIN-1-ONE DERIVATIVES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER

This invention relates to compounds of general Formula (I)and pharmaceutically acceptable salts thereof, in which R1, R1a, R2, R3, R4, and (R5)a are as defined herein, to pharmaceutical compositions comprising such compounds and pharmaceutically acceptable salts thereof, and to methods of using such...

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Bibliographische Detailangaben

Hauptverfasser:	JALAIE, Mehran, ZHOU, Ru, TUTTLE, Jamison Bryce, MCTIGUE, Michele Ann, NAIR, Sajiv Krishnan, ZHOU, Dahui, SCHMITT, Anne-Marie Dechert, AHMAD, Omar Khaled, JOHNSON, Ted William, HE, Mingying, DEL BEL, Matthew L, GALLEGO, Rebecca Anne, KANIA, Robert Steven
Format:	Patent
Sprache:	eng ; hun
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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