CRYSTALLINE MONOHYDRATE COMPLEX OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(BETA-D-GLUCOPYRANOS-1-YL)-BENZENE AND L-PROLINE IN CRYSTAL WATER (1:1:1), METHODS FOR ITS PREPARATION AND ITS USE AS AN SGLT INHIBITOR

The invention relates to a mixture of crystalline forms comprising a crystalline monohydrate complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene (compound A) and L-Proline in admixture with another form or forms of compound A.

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Hauptverfasser:	MARTIN, Hans-Juergen, BUTZ, Tanja Maria, HIMMELSBACH, Frank, ECKHARDT, Matthias
Format:	Patent
Sprache:	eng ; hun
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	MARTIN, Hans-Juergen BUTZ, Tanja Maria HIMMELSBACH, Frank ECKHARDT, Matthias
description	The invention relates to a mixture of crystalline forms comprising a crystalline monohydrate complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene (compound A) and L-Proline in admixture with another form or forms of compound A.
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	CRYSTALLINE MONOHYDRATE COMPLEX OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(BETA-D-GLUCOPYRANOS-1-YL)-BENZENE AND L-PROLINE IN CRYSTAL WATER (1:1:1), METHODS FOR ITS PREPARATION AND ITS USE AS AN SGLT INHIBITOR
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