METHYLENE CARBAMATE LINKERS FOR USE WITH TARGETED-DRUG CONJUGATES

The present invention provides Ligand-Drug Conjugates and Drug-Linker Compounds comprising a methylene carbamate unit. The invention provides inter alia, Ligand-Drug Conjugates, wherein the Ligand-Drug Conjugate is comprised of a Self-immolative Assembly Unit having a methylene carbamate unit for co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KOLAKOWSKI, Robert, JEFFREY, Scott, BURKE, Patrick
Format: Patent
Sprache:eng ; hun
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