ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reactio...
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| creator | Norregaard-Madsen, Mads SAMS, Christian Klarner PEDERSEN, Henrik HOLTMANN, Anette FRESKGARD, Per-Ola DE LEON, Dean Andersen, Anne Lee KALDOR, Ditte Kievsmose HUSEMOEN, Gitte Nystrup Godskesen, Michael Anders Dolberg, Johannes Kronberg, Tine Titilola Akinleminu Jensen, Kim Birkebaek PETERSEN, Lene JAKOBSEN, Soren Nyboe THISTED, Thomas Sorensen, Anders Malling GOLDBECH, Anne Glad, Sanne Schroder Slok, Frank Abildgaard Olsen, Eva Kampmann Neve, Soren GOLIAEV, Alex Haahr LUNDORF, Mikkel Dybro HANSEN, Anders Holm Franch, Thomas Felding, Jakob |
| description | Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s). |
| format | Patent |
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Kronberg, Tine Titilola Akinleminu ; Jensen, Kim Birkebaek ; PETERSEN, Lene ; JAKOBSEN, Soren Nyboe ; THISTED, Thomas ; Sorensen, Anders Malling ; GOLDBECH, Anne ; Glad, Sanne Schroder ; Slok, Frank Abildgaard ; Olsen, Eva Kampmann ; Neve, Soren ; GOLIAEV, Alex Haahr ; LUNDORF, Mikkel Dybro ; HANSEN, Anders Holm ; Franch, Thomas ; Felding, Jakob</creator><creatorcontrib>Norregaard-Madsen, Mads ; SAMS, Christian Klarner ; PEDERSEN, Henrik ; HOLTMANN, Anette ; FRESKGARD, Per-Ola ; DE LEON, Dean ; Andersen, Anne Lee ; KALDOR, Ditte Kievsmose ; HUSEMOEN, Gitte Nystrup ; Godskesen, Michael Anders ; Dolberg, Johannes ; Kronberg, Tine Titilola Akinleminu ; Jensen, Kim Birkebaek ; PETERSEN, Lene ; JAKOBSEN, Soren Nyboe ; THISTED, Thomas ; Sorensen, Anders Malling ; GOLDBECH, Anne ; Glad, Sanne Schroder ; Slok, Frank Abildgaard ; Olsen, Eva Kampmann ; Neve, Soren ; GOLIAEV, Alex Haahr ; LUNDORF, Mikkel Dybro ; HANSEN, Anders Holm ; Franch, Thomas ; Felding, Jakob</creatorcontrib><description>Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).</description><language>eng ; hun</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMBINATORIAL CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF 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Christian Klarner</au><au>PEDERSEN, Henrik</au><au>HOLTMANN, Anette</au><au>FRESKGARD, Per-Ola</au><au>DE LEON, Dean</au><au>Andersen, Anne Lee</au><au>KALDOR, Ditte Kievsmose</au><au>HUSEMOEN, Gitte Nystrup</au><au>Godskesen, Michael Anders</au><au>Dolberg, Johannes</au><au>Kronberg, Tine Titilola Akinleminu</au><au>Jensen, Kim Birkebaek</au><au>PETERSEN, Lene</au><au>JAKOBSEN, Soren Nyboe</au><au>THISTED, Thomas</au><au>Sorensen, Anders Malling</au><au>GOLDBECH, Anne</au><au>Glad, Sanne Schroder</au><au>Slok, Frank Abildgaard</au><au>Olsen, Eva Kampmann</au><au>Neve, Soren</au><au>GOLIAEV, Alex Haahr</au><au>LUNDORF, Mikkel Dybro</au><au>HANSEN, Anders Holm</au><au>Franch, Thomas</au><au>Felding, Jakob</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES</title><date>2022-03-28</date><risdate>2022</risdate><abstract>Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES |
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