TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE

Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast canc...

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Hauptverfasser: HAO, Ming-Hong, PUYANG, Xiaoling, KORPAL, Manav, NYAVANANDI, Vijay Kumar, BOCK, Mark
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creator HAO, Ming-Hong
PUYANG, Xiaoling
KORPAL, Manav
NYAVANANDI, Vijay Kumar
BOCK, Mark
description Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE
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