HIGH AFFINITY PD-1 AGENTS AND METHODS OF USE

High affinity PD-1 mimic polypeptides are provided, which (i) comprise at least one amino acid change relative to a wild-type PD-1 protein; and (ii) have an increased affinity for PD-L1 relative to the wild-type protein. Compositions and methods are provided for modulating the activity of immune cel...

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Bibliographische Detailangaben

Hauptverfasser:	WEISSMAN, Irving L, RING, Aaron Michael, MCCRACKEN, Melissa N, GORDON, Sydney, KRUSE, Andrew, MANGLIK, Aashish, MAUTE, Roy Louis
Format:	Patent
Sprache:	eng ; hun
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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