REDUCING PROTEIN A LEACHING DURING PROTEIN A AFFINITY CHROMATOGRAPHY

A method for reducing leaching of protein A during protein A affinity chromatography is described which involves reducing temperature of pH of, or by adding one or more protease inhibitors to, a composition that is subject to protein A affinity chromatography.

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Hauptverfasser: FAHRNER, Robert L, McDonald, Paul J, O'LEARY, Rhona M, LAVERDIERE, Amy
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Sprache:eng ; hun
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creator FAHRNER, Robert L
McDonald, Paul J
O'LEARY, Rhona M
LAVERDIERE, Amy
description A method for reducing leaching of protein A during protein A affinity chromatography is described which involves reducing temperature of pH of, or by adding one or more protease inhibitors to, a composition that is subject to protein A affinity chromatography.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title REDUCING PROTEIN A LEACHING DURING PROTEIN A AFFINITY CHROMATOGRAPHY
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