NOVEL MUCOSAL ADJUVANTS AND DELIVERY SYSTEMS

NOVEL MUCOSAL ADJUVANTS AND DELIVERY SYSTEMS

Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the v...

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Hauptverfasser: MORGAN, Marion, PUMFORD, Neil, WOLFENDEN, Amanda, TELLEZ, Guillermo, HARGIS, Billy, SHIVARAMAIAH, Srichaitanya
Format: Patent
Sprache:eng ; hun
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CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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creator MORGAN, Marion
PUMFORD, Neil
WOLFENDEN, Amanda
TELLEZ, Guillermo
HARGIS, Billy
SHIVARAMAIAH, Srichaitanya
description Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.
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subjects CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title NOVEL MUCOSAL ADJUVANTS AND DELIVERY SYSTEMS
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