METHOD FOR PRODUCING HIGH-CONCENTRATION COLLAGEN FOR USING AS MEDICAL MATERIAL
The present invention relates to a method for producing a high-concentration collagen for using as a medical material. After washing tissues of a mammal, the washed tissues of the mammal are grinded and deposited in ethyl alcohol, and an enzyme is treated by putting phosphoric acid in purified water...
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creator | CHANG, Cheong Ho |
description | The present invention relates to a method for producing a high-concentration collagen for using as a medical material. After washing tissues of a mammal, the washed tissues of the mammal are grinded and deposited in ethyl alcohol, and an enzyme is treated by putting phosphoric acid in purified water, and then putting pepsin therein and stirring and reacting same, and collagen is coagulated by means of adding sodium chloride to the enzyme-treated collagen and stirring same, and the coagulated collagen is dissolved using purified water and then filtered using a filter, and pepsin, low-molecular materials, and sodium chloride in the solution are removed by using a tangential flow filtration device, and the collagen is concentrated. The concentrated collagen is sterilized and filtered, and the collagen is coagulated by using a neutralization reaction tank and a pH solution, and uncoagulated solution is removed, and then the collagen is concentrated, and the concentrated collagen is concentrated by using a centrifuge, and the concentrated collagen is put in a mixer and then stirred, and thus a high-concentration collagen is produced and used as a medical material. |
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After washing tissues of a mammal, the washed tissues of the mammal are grinded and deposited in ethyl alcohol, and an enzyme is treated by putting phosphoric acid in purified water, and then putting pepsin therein and stirring and reacting same, and collagen is coagulated by means of adding sodium chloride to the enzyme-treated collagen and stirring same, and the coagulated collagen is dissolved using purified water and then filtered using a filter, and pepsin, low-molecular materials, and sodium chloride in the solution are removed by using a tangential flow filtration device, and the collagen is concentrated. The concentrated collagen is sterilized and filtered, and the collagen is coagulated by using a neutralization reaction tank and a pH solution, and uncoagulated solution is removed, and then the collagen is concentrated, and the concentrated collagen is concentrated by using a centrifuge, and the concentrated collagen is put in a mixer and then stirred, and thus a high-concentration collagen is produced and used as a medical material.</description><language>eng ; hun</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201028&DB=EPODOC&CC=HU&NR=E049757T2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201028&DB=EPODOC&CC=HU&NR=E049757T2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHANG, Cheong Ho</creatorcontrib><title>METHOD FOR PRODUCING HIGH-CONCENTRATION COLLAGEN FOR USING AS MEDICAL MATERIAL</title><description>The present invention relates to a method for producing a high-concentration collagen for using as a medical material. 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After washing tissues of a mammal, the washed tissues of the mammal are grinded and deposited in ethyl alcohol, and an enzyme is treated by putting phosphoric acid in purified water, and then putting pepsin therein and stirring and reacting same, and collagen is coagulated by means of adding sodium chloride to the enzyme-treated collagen and stirring same, and the coagulated collagen is dissolved using purified water and then filtered using a filter, and pepsin, low-molecular materials, and sodium chloride in the solution are removed by using a tangential flow filtration device, and the collagen is concentrated. The concentrated collagen is sterilized and filtered, and the collagen is coagulated by using a neutralization reaction tank and a pH solution, and uncoagulated solution is removed, and then the collagen is concentrated, and the concentrated collagen is concentrated by using a centrifuge, and the concentrated collagen is put in a mixer and then stirred, and thus a high-concentration collagen is produced and used as a medical material.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC CHEMISTRY PEPTIDES |
title | METHOD FOR PRODUCING HIGH-CONCENTRATION COLLAGEN FOR USING AS MEDICAL MATERIAL |
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