PYRAZOLO[1,5-A]PYRAZIN-4-YL DERIVATIVES AS JAK-INHIBITORS

A compound having the structure:or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or pharmaceutically acceptable salt, wherein A, A', A", R0, R, R1, R2, X, R4, and R5, are as defined in the description, for therapeutic use, wherein whe...

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Hauptverfasser: HAYWARD, Matthew Merrill, WRIGHT, Stephen Wayne, OWEN, Dafydd Rhys, DERMENCI, Alpay, FENSOME, Andrew, GERSTENBERGER, Brian Stephen, XING, Li Huang, YANG, Xiaojing, BROWN, Matthew Frank
Format: Patent
Sprache:eng ; hun
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Zusammenfassung:A compound having the structure:or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or pharmaceutically acceptable salt, wherein A, A', A", R0, R, R1, R2, X, R4, and R5, are as defined in the description, for therapeutic use, wherein where the compound, or the pharmaceutically acceptable salt thereof, or the pharmaceutically acceptable solvate of said compound or pharmaceutically acceptable salt, is administered orally.