2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS

2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: JOHNSON JR., Theodore Otto, KATH, John Charles, CHO-SCHULTZ, Sujin, PLANKEN, Simon Paul, NAGATA, Asako, CHENG, Hengmiao, NAIR, Sajiv Krishnan, BEHENNA, Douglas Carl
Format: Patent
Sprache:eng ; hun
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator JOHNSON JR., Theodore Otto
KATH, John Charles
CHO-SCHULTZ, Sujin
PLANKEN, Simon Paul
NAGATA, Asako
CHENG, Hengmiao
NAIR, Sajiv Krishnan
BEHENNA, Douglas Carl
description The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_HUE039858TT2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>HUE039858TT2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_HUE039858TT23</originalsourceid><addsrcrecordid>eNqNjMsKwjAQRbNxIeo_jHsL0qLUZTQTMqBJmUy6EkqRuBIt1P_HB36Aq8uBc-5UncvVtohpH4UkCRpoEpNHMMjUaqEWI2hvQBwSQ4oI5D8AwqjlhF4gWGg4HMkifwMwFAO_D-JcTa79bcyL387U0qIcXJGHR5fHob_ke352LuG62tWbWqSs_nFexv0zGw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS</title><source>esp@cenet</source><creator>JOHNSON JR., Theodore Otto ; KATH, John Charles ; CHO-SCHULTZ, Sujin ; PLANKEN, Simon Paul ; NAGATA, Asako ; CHENG, Hengmiao ; NAIR, Sajiv Krishnan ; BEHENNA, Douglas Carl</creator><creatorcontrib>JOHNSON JR., Theodore Otto ; KATH, John Charles ; CHO-SCHULTZ, Sujin ; PLANKEN, Simon Paul ; NAGATA, Asako ; CHENG, Hengmiao ; NAIR, Sajiv Krishnan ; BEHENNA, Douglas Carl</creatorcontrib><description>The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.</description><language>eng ; hun</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20190228&amp;DB=EPODOC&amp;CC=HU&amp;NR=E039858T2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20190228&amp;DB=EPODOC&amp;CC=HU&amp;NR=E039858T2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JOHNSON JR., Theodore Otto</creatorcontrib><creatorcontrib>KATH, John Charles</creatorcontrib><creatorcontrib>CHO-SCHULTZ, Sujin</creatorcontrib><creatorcontrib>PLANKEN, Simon Paul</creatorcontrib><creatorcontrib>NAGATA, Asako</creatorcontrib><creatorcontrib>CHENG, Hengmiao</creatorcontrib><creatorcontrib>NAIR, Sajiv Krishnan</creatorcontrib><creatorcontrib>BEHENNA, Douglas Carl</creatorcontrib><title>2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS</title><description>The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjMsKwjAQRbNxIeo_jHsL0qLUZTQTMqBJmUy6EkqRuBIt1P_HB36Aq8uBc-5UncvVtohpH4UkCRpoEpNHMMjUaqEWI2hvQBwSQ4oI5D8AwqjlhF4gWGg4HMkifwMwFAO_D-JcTa79bcyL387U0qIcXJGHR5fHob_ke352LuG62tWbWqSs_nFexv0zGw</recordid><startdate>20190228</startdate><enddate>20190228</enddate><creator>JOHNSON JR., Theodore Otto</creator><creator>KATH, John Charles</creator><creator>CHO-SCHULTZ, Sujin</creator><creator>PLANKEN, Simon Paul</creator><creator>NAGATA, Asako</creator><creator>CHENG, Hengmiao</creator><creator>NAIR, Sajiv Krishnan</creator><creator>BEHENNA, Douglas Carl</creator><scope>EVB</scope></search><sort><creationdate>20190228</creationdate><title>2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS</title><author>JOHNSON JR., Theodore Otto ; KATH, John Charles ; CHO-SCHULTZ, Sujin ; PLANKEN, Simon Paul ; NAGATA, Asako ; CHENG, Hengmiao ; NAIR, Sajiv Krishnan ; BEHENNA, Douglas Carl</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HUE039858TT23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; hun</language><creationdate>2019</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>JOHNSON JR., Theodore Otto</creatorcontrib><creatorcontrib>KATH, John Charles</creatorcontrib><creatorcontrib>CHO-SCHULTZ, Sujin</creatorcontrib><creatorcontrib>PLANKEN, Simon Paul</creatorcontrib><creatorcontrib>NAGATA, Asako</creatorcontrib><creatorcontrib>CHENG, Hengmiao</creatorcontrib><creatorcontrib>NAIR, Sajiv Krishnan</creatorcontrib><creatorcontrib>BEHENNA, Douglas Carl</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JOHNSON JR., Theodore Otto</au><au>KATH, John Charles</au><au>CHO-SCHULTZ, Sujin</au><au>PLANKEN, Simon Paul</au><au>NAGATA, Asako</au><au>CHENG, Hengmiao</au><au>NAIR, Sajiv Krishnan</au><au>BEHENNA, Douglas Carl</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS</title><date>2019-02-28</date><risdate>2019</risdate><abstract>The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; hun
recordid cdi_epo_espacenet_HUE039858TT2
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 2,6-SUBSTITUTED PURINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T04%3A50%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=JOHNSON%20JR.,%20Theodore%20Otto&rft.date=2019-02-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EHUE039858TT2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true