INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK

INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK

The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, o...

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Hauptverfasser: FILIPSKI, Kevin James, FERNANDO, Dilinie Prasadhini, CAMERON, Kimberly O'Keefe, LEE, Esther Cheng Yin, EBNER, David Christopher, TU, Meihua Mike, DOWLING, Matthew Scott, BHATTACHARYA, Samit Kumar, SMITH, Aaron Christopher, KUNG, Daniel Wei-Shung
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Sprache:eng ; hun
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator FILIPSKI, Kevin James
FERNANDO, Dilinie Prasadhini
CAMERON, Kimberly O'Keefe
LEE, Esther Cheng Yin
EBNER, David Christopher
TU, Meihua Mike
DOWLING, Matthew Scott
BHATTACHARYA, Samit Kumar
SMITH, Aaron Christopher
KUNG, Daniel Wei-Shung
description The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK
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