Heterocyclic modulators of ATP-binding cassette transporters

Heterocyclic modulators of ATP-binding cassette transporters

Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also...

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Hauptverfasser: HAMILTON, Matthew, ZHOU, Jinglan, Hadida Ruah, Sarah, Miller, Mark, Grootenhuis, Peter D. J, McCarthy, Jason, BEAR, Brian
Format: Patent
Sprache:eng ; hun
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator HAMILTON, Matthew
ZHOU, Jinglan
Hadida Ruah, Sarah
Miller, Mark
Grootenhuis, Peter D. J
McCarthy, Jason
BEAR, Brian
description Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention..
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Heterocyclic modulators of ATP-binding cassette transporters
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