SLOW RELEASE PHARMACEUTICAL COMPOSITION MADE OF MICROPARTICLES
Pharmaceutical composition made of microparticles for the slow release of an active substance at least during a period covering the 6 th month after injection of said composition, said composition comprising a group of microparticles made of a copolymer of the PLGA type which incorporate an active s...
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creator | DUCREY, Bertrand HEIMGARTNER, Frederic PORCHET, Herve LUNDSTROM, Eija BARDET, Marie-Anne CURDY, Catherine GARROUSTE, Patrick |
description | Pharmaceutical composition made of microparticles for the slow release of an active substance at least during a period covering the 6 th month after injection of said composition, said composition comprising a group of microparticles made of a copolymer of the PLGA type which incorporate an active substance in the form of a water insoluble peptide salt; said copolymer furthermore comprising at least 75 % of lactic acid and an inherent viscosity between 0.1 and 0.9 dl/g, as measured in chloroform at 25 °C and at a polymer concentration of 0.5 g/dL; said microparticles furthermore having a size distribution defined as follows :
- D (v,0.1) is between 10 and 30 micrometers,
- D (v,0.5) is between 30 and 70 micrometers,
- D(v,0.9) is between 50 and 110 micrometers. |
format | Patent |
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- D (v,0.1) is between 10 and 30 micrometers,
- D (v,0.5) is between 30 and 70 micrometers,
- D(v,0.9) is between 50 and 110 micrometers.</description><language>eng ; hun</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170728&DB=EPODOC&CC=HU&NR=E031550T2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170728&DB=EPODOC&CC=HU&NR=E031550T2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DUCREY, Bertrand</creatorcontrib><creatorcontrib>HEIMGARTNER, Frederic</creatorcontrib><creatorcontrib>PORCHET, Herve</creatorcontrib><creatorcontrib>LUNDSTROM, Eija</creatorcontrib><creatorcontrib>BARDET, Marie-Anne</creatorcontrib><creatorcontrib>CURDY, Catherine</creatorcontrib><creatorcontrib>GARROUSTE, Patrick</creatorcontrib><title>SLOW RELEASE PHARMACEUTICAL COMPOSITION MADE OF MICROPARTICLES</title><description>Pharmaceutical composition made of microparticles for the slow release of an active substance at least during a period covering the 6 th month after injection of said composition, said composition comprising a group of microparticles made of a copolymer of the PLGA type which incorporate an active substance in the form of a water insoluble peptide salt; said copolymer furthermore comprising at least 75 % of lactic acid and an inherent viscosity between 0.1 and 0.9 dl/g, as measured in chloroform at 25 °C and at a polymer concentration of 0.5 g/dL; said microparticles furthermore having a size distribution defined as follows :
- D (v,0.1) is between 10 and 30 micrometers,
- D (v,0.5) is between 30 and 70 micrometers,
- D(v,0.9) is between 50 and 110 micrometers.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAL9vEPVwhy9XF1DHZVCPBwDPJ1dHYNDfF0dvRRcPb3DfAP9gzx9PdT8HV0cVXwd1Pw9XQO8g9wDAKq8HEN5mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8R6hrgbGhqamBiEhRsbEqAEAfmYq3w</recordid><startdate>20170728</startdate><enddate>20170728</enddate><creator>DUCREY, Bertrand</creator><creator>HEIMGARTNER, Frederic</creator><creator>PORCHET, Herve</creator><creator>LUNDSTROM, Eija</creator><creator>BARDET, Marie-Anne</creator><creator>CURDY, Catherine</creator><creator>GARROUSTE, Patrick</creator><scope>EVB</scope></search><sort><creationdate>20170728</creationdate><title>SLOW RELEASE PHARMACEUTICAL COMPOSITION MADE OF MICROPARTICLES</title><author>DUCREY, Bertrand ; HEIMGARTNER, Frederic ; PORCHET, Herve ; LUNDSTROM, Eija ; BARDET, Marie-Anne ; CURDY, Catherine ; GARROUSTE, Patrick</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HUE031550TT23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; hun</language><creationdate>2017</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>DUCREY, Bertrand</creatorcontrib><creatorcontrib>HEIMGARTNER, Frederic</creatorcontrib><creatorcontrib>PORCHET, Herve</creatorcontrib><creatorcontrib>LUNDSTROM, Eija</creatorcontrib><creatorcontrib>BARDET, Marie-Anne</creatorcontrib><creatorcontrib>CURDY, Catherine</creatorcontrib><creatorcontrib>GARROUSTE, Patrick</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DUCREY, Bertrand</au><au>HEIMGARTNER, Frederic</au><au>PORCHET, Herve</au><au>LUNDSTROM, Eija</au><au>BARDET, Marie-Anne</au><au>CURDY, Catherine</au><au>GARROUSTE, Patrick</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SLOW RELEASE PHARMACEUTICAL COMPOSITION MADE OF MICROPARTICLES</title><date>2017-07-28</date><risdate>2017</risdate><abstract>Pharmaceutical composition made of microparticles for the slow release of an active substance at least during a period covering the 6 th month after injection of said composition, said composition comprising a group of microparticles made of a copolymer of the PLGA type which incorporate an active substance in the form of a water insoluble peptide salt; said copolymer furthermore comprising at least 75 % of lactic acid and an inherent viscosity between 0.1 and 0.9 dl/g, as measured in chloroform at 25 °C and at a polymer concentration of 0.5 g/dL; said microparticles furthermore having a size distribution defined as follows :
- D (v,0.1) is between 10 and 30 micrometers,
- D (v,0.5) is between 30 and 70 micrometers,
- D(v,0.9) is between 50 and 110 micrometers.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | SLOW RELEASE PHARMACEUTICAL COMPOSITION MADE OF MICROPARTICLES |
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