FUSED QUINONIC COMPOUNDS

FUSED QUINONIC COMPOUNDS

A compound having the formula (I): for use in treating disease; a composition comprising said fused quinonic compound of formula (I) and at least one pharmaceutically acceptable carrier; as well as a method of modulating a Janus Kinase-Signal Transduction and Activators of Transcription (JAK-STAT) p...

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Hauptverfasser: McNAUGHTON SMITH, Grant, JIMENEZ ALONSO, Sandra, DIAZ CHICO, Bonifacio Nicolas, GUTIERREZ RAVELO, Angel Domingo, ESTEVEZ BRAUN, Ana, FERNANDEZ PEREZ, Leandro
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Sprache:eng ; hun
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creator McNAUGHTON SMITH, Grant
JIMENEZ ALONSO, Sandra
DIAZ CHICO, Bonifacio Nicolas
GUTIERREZ RAVELO, Angel Domingo
ESTEVEZ BRAUN, Ana
FERNANDEZ PEREZ, Leandro
description A compound having the formula (I): for use in treating disease; a composition comprising said fused quinonic compound of formula (I) and at least one pharmaceutically acceptable carrier; as well as a method of modulating a Janus Kinase-Signal Transduction and Activators of Transcription (JAK-STAT) pathway. The activation of a JAK-STAT pathway is associated with several disease states such as immunological and inflammatory diseases, hyperproliferative disorders including cancer, and myeloproliferative diseases.
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