METHOD FOR THE MANUFACTURE OF DEGARELIX

In a step-wise synthesis of degarelix comprising 0.3% by weight or less of 4-([2-(5-hydantoyl)]acetylamino)-phenylalanine analog on (solid support)-NH2 a step comprises providing a solution of an amino acid or peptide of which the α-amino group is protected by Fmoc; contacting the support with the s...

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Hauptverfasser: FOMSGAARD, Jens, ZHANG, Haixiang, STAERKAER, Gunnar
Format: Patent
Sprache:eng ; hun
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