Hydroxamate derivatives useful as deacetylase inhibitors and pharmaceutical compositions containing them

The present invention provides hydroxamate compounds of formula I: which are deacetylase inhibitors. The compounds are suitable for pharmaceutical compositions having anti-proliferative properties.

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Hauptverfasser: BAIR KENNETH WALTER MOUNTAIN LAKES, GREEN MICHAEL A. EASTON, PEREZ LAWRENCE B. HACKETTSTOWN, SHARMA SUSHIL KUMAR WEST ORANGE, VERSACE RICHARD WILLIAM WANAQUE, REMISZEWSKI STACY W. WASHINGTON TOWNSHIP, SAMBUCETTI LIDIA PACIFICA
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creator BAIR KENNETH WALTER MOUNTAIN LAKES
GREEN MICHAEL A. EASTON
PEREZ LAWRENCE B. HACKETTSTOWN
SHARMA SUSHIL KUMAR WEST ORANGE
VERSACE RICHARD WILLIAM WANAQUE
REMISZEWSKI STACY W. WASHINGTON TOWNSHIP
SAMBUCETTI LIDIA PACIFICA
description The present invention provides hydroxamate compounds of formula I: which are deacetylase inhibitors. The compounds are suitable for pharmaceutical compositions having anti-proliferative properties.
format Patent
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Hydroxamate derivatives useful as deacetylase inhibitors and pharmaceutical compositions containing them
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