Calcium salt of (3s) tetrahydro-3-furanyl(1s,2r)-3-[[(4-aminophenyl)sulfonyl]-(isobutyl)amino]-1-benzyl-2-(phosphonooxy) propylcarbamate, pharmaceutical composition containing the compound and process for preparation the same

The invention relates to calcium (3S) tetrahydro-3-furanyl(1S,2R)-3-ÄÄ(4-aminophenyl)sulfonylÜ(isobutyl)amin oÜ-1-benzyl-2-(phosphonooxy) propylcarbamate combined with the HIV protease inhibitor 10-hydroxy-2-methyl-5-(1-methylethyl)-1-Ä2-(1-methylethyl)4-thiazolylÜ -3,6-dioxo-8,1 1-bis(phenylmethyl)...

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Hauptverfasser: ARMITAGE IAN GORDON ARLESEY, SEARLE ANDREW DAVID STEVENAGE, SINGH HARDEV DARTFORD
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creator ARMITAGE IAN GORDON ARLESEY
SEARLE ANDREW DAVID STEVENAGE
SINGH HARDEV DARTFORD
description The invention relates to calcium (3S) tetrahydro-3-furanyl(1S,2R)-3-ÄÄ(4-aminophenyl)sulfonylÜ(isobutyl)amin oÜ-1-benzyl-2-(phosphonooxy) propylcarbamate combined with the HIV protease inhibitor 10-hydroxy-2-methyl-5-(1-methylethyl)-1-Ä2-(1-methylethyl)4-thiazolylÜ -3,6-dioxo-8,1 1-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic acid, 5-thiazolylmethyl ester (ritonavir), and to the use thereof in the treatment of diseases caused by retroviruses.
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Calcium salt of (3s) tetrahydro-3-furanyl(1s,2r)-3-[[(4-aminophenyl)sulfonyl]-(isobutyl)amino]-1-benzyl-2-(phosphonooxy) propylcarbamate, pharmaceutical composition containing the compound and process for preparation the same
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