NOVEL SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE
PCT No. PCT/EP95/04843 Sec. 371 Date Aug. 15, 1997 Sec. 102(e) Date Aug. 15, 1997 PCT Filed Dec. 8, 1995 PCT Pub. No. WO96/19459 PCT Pub. Date Jun. 27, 1996Compounds of the formula: where A, B, R1-R8 are as described herein are endothelin inhibitors that can be used in treating diseases associated w...
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| creator | NEIDHART, WERNER CLOZEL, MARTINE MUELLER, MARCEL CASSAL, JEAN-MARIE BREU, VOLKER BURRI, KASPAR LOEFFLER, BERND-MICHAEL HIRTH, GEORGES RAMUZ, HENRI |
| description | PCT No. PCT/EP95/04843 Sec. 371 Date Aug. 15, 1997 Sec. 102(e) Date Aug. 15, 1997 PCT Filed Dec. 8, 1995 PCT Pub. No. WO96/19459 PCT Pub. Date Jun. 27, 1996Compounds of the formula: where A, B, R1-R8 are as described herein are endothelin inhibitors that can be used in treating diseases associated with endothelin, such as high blood pressure. Chemical synthesis of these compounds and pharmaceutical compositions containing these compounds are also useful. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NOVEL SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE |
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