PROCESS FOR DEHYDROGENATION OF AZA-ANDROSTANE COMPOUNDS

PROCESS FOR DEHYDROGENATION OF AZA-ANDROSTANE COMPOUNDS

The invention relates to a process for the production of compounds of general formula (I), wherein R1 is a -NH-tert-butyl group or a 4-methyl-piperidino group, by bioconversion of compounds of general formula (II), wherein R1 is as described above, using a biocatalyst having steroid-Delta -dehydroge...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PECSNE RAZSO AGNES, BARTHO ISTVAN, BERTA MONIKA, DEVENYI TAMAS, HANTOS GABOR DR, OLASZ KATALIN DR
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
SPIRITS
STEROIDS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention relates to a process for the production of compounds of general formula (I), wherein R1 is a -NH-tert-butyl group or a 4-methyl-piperidino group, by bioconversion of compounds of general formula (II), wherein R1 is as described above, using a biocatalyst having steroid-Delta -dehydrogenase enzyme activity, wherein the activity of the enzyme needed for the bioconversion is produced by induction.