PROCESS FOR PRODUCING OXA-PROSTAGLANDINES

Cyclopentane derivatives of the formula: wherein R1 represents alkyl of 1 through 4 carbon atoms, R2 represents hydrogen or alkyl of 1 through 3 carbon atoms, R3 represents alkoxy of 3 through 6 carbon atoms, or alkoxyalkyl in which alkoxy and alkyl moieties each contain 1 through 4 carbon atoms, R4...

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Hauptverfasser: CATON,MICHAEL P. L.,GB, COFFEE,EDWARD C. J.,GB, WATKINS,GORDON L.,GB
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creator CATON,MICHAEL P. L.,GB
COFFEE,EDWARD C. J.,GB
WATKINS,GORDON L.,GB
description Cyclopentane derivatives of the formula: wherein R1 represents alkyl of 1 through 4 carbon atoms, R2 represents hydrogen or alkyl of 1 through 3 carbon atoms, R3 represents alkoxy of 3 through 6 carbon atoms, or alkoxyalkyl in which alkoxy and alkyl moieties each contain 1 through 4 carbon atoms, R4 represents hydrogen or alkyl of 1 through 12 carbon atoms, R5 represents hydrogen or alkyl of 1 through 4 carbon atoms or a carboxylic acyl group, A represents carbonyl or a group -CH(OR5)- wherein R5 is as hereinbefore defined, and X represents ethylene or trans-vinylene, possess pharmacological properties, for example the production of hypotension, broncodilation, inhibition of gastric acid secretion, and stimulation of uterine contraction.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR PRODUCING OXA-PROSTAGLANDINES
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