NITRATOALKANECARBONE ACID DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THE USE OF THE SAME AND DRUGS CONTAINING THEM

Nitratoalkanoic acid derivatives of the general formula (I), in particular containing N-acylamino acids or N-acylpeptides, of the general formula (I) in which the symbols have the meanings mentioned in the claims. They are distinguished by advantageous physicochemical properties and good physiologic...

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Hauptverfasser: EIKE NOACK, EDGAR FRITSCHI, RALF KANZLER, KLAUS SANDROCK, MARTIN FEELISCH
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creator EIKE NOACK
EDGAR FRITSCHI
RALF KANZLER
KLAUS SANDROCK
MARTIN FEELISCH
description Nitratoalkanoic acid derivatives of the general formula (I), in particular containing N-acylamino acids or N-acylpeptides, of the general formula (I) in which the symbols have the meanings mentioned in the claims. They are distinguished by advantageous physicochemical properties and good physiological tolerability for active substances already preventing known nitrate tolerance or weakening a tolerance which has already set in. The compounds are used in medicaments for the treatment of circulatory disorders, high blood pressure, cardiac insufficiency and for dilating the peripheral vessels.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NITRATOALKANECARBONE ACID DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THE USE OF THE SAME AND DRUGS CONTAINING THEM
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