TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS

The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1 C3 dependent KARS inhibitor.

Bibliographische Detailangaben

Hauptverfasser:	Savage, Nik, Adair, Chris, Larraufie, Marie-Helene, Nakajima, Katsumasa, Isome, Yuko, Fryer, Christy, Chen, Tracy, Twomey, Ariel Sterling, Ding, Jian
Format:	Patent
Sprache:	hrv ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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