TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS
The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1 C3 dependent KARS inhibitor.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | hrv ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Savage, Nik Adair, Chris Larraufie, Marie-Helene Nakajima, Katsumasa Isome, Yuko Fryer, Christy Chen, Tracy Twomey, Ariel Sterling Ding, Jian |
| description | The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1 C3 dependent KARS inhibitor. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_HRP20231734TT1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>HRP20231734TT1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_HRP20231734TT13</originalsourceid><addsrcrecordid>eNrjZNAKCfJ0jnT28XRWcPQOMnQ2VnBxDXD1c3H1C1HwdgwKVvD08_B08gzxDwrmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxHkEBRgZGxobmxiYhIYbGxKkCAN4pJfE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS</title><source>esp@cenet</source><creator>Savage, Nik ; Adair, Chris ; Larraufie, Marie-Helene ; Nakajima, Katsumasa ; Isome, Yuko ; Fryer, Christy ; Chen, Tracy ; Twomey, Ariel Sterling ; Ding, Jian</creator><creatorcontrib>Savage, Nik ; Adair, Chris ; Larraufie, Marie-Helene ; Nakajima, Katsumasa ; Isome, Yuko ; Fryer, Christy ; Chen, Tracy ; Twomey, Ariel Sterling ; Ding, Jian</creatorcontrib><description>The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1 C3 dependent KARS inhibitor.</description><language>hrv ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240315&DB=EPODOC&CC=HR&NR=P20231734T1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240315&DB=EPODOC&CC=HR&NR=P20231734T1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Savage, Nik</creatorcontrib><creatorcontrib>Adair, Chris</creatorcontrib><creatorcontrib>Larraufie, Marie-Helene</creatorcontrib><creatorcontrib>Nakajima, Katsumasa</creatorcontrib><creatorcontrib>Isome, Yuko</creatorcontrib><creatorcontrib>Fryer, Christy</creatorcontrib><creatorcontrib>Chen, Tracy</creatorcontrib><creatorcontrib>Twomey, Ariel Sterling</creatorcontrib><creatorcontrib>Ding, Jian</creatorcontrib><title>TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS</title><description>The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1 C3 dependent KARS inhibitor.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAKCfJ0jnT28XRWcPQOMnQ2VnBxDXD1c3H1C1HwdgwKVvD08_B08gzxDwrmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxHkEBRgZGxobmxiYhIYbGxKkCAN4pJfE</recordid><startdate>20240315</startdate><enddate>20240315</enddate><creator>Savage, Nik</creator><creator>Adair, Chris</creator><creator>Larraufie, Marie-Helene</creator><creator>Nakajima, Katsumasa</creator><creator>Isome, Yuko</creator><creator>Fryer, Christy</creator><creator>Chen, Tracy</creator><creator>Twomey, Ariel Sterling</creator><creator>Ding, Jian</creator><scope>EVB</scope></search><sort><creationdate>20240315</creationdate><title>TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS</title><author>Savage, Nik ; Adair, Chris ; Larraufie, Marie-Helene ; Nakajima, Katsumasa ; Isome, Yuko ; Fryer, Christy ; Chen, Tracy ; Twomey, Ariel Sterling ; Ding, Jian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HRP20231734TT13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>hrv ; eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Savage, Nik</creatorcontrib><creatorcontrib>Adair, Chris</creatorcontrib><creatorcontrib>Larraufie, Marie-Helene</creatorcontrib><creatorcontrib>Nakajima, Katsumasa</creatorcontrib><creatorcontrib>Isome, Yuko</creatorcontrib><creatorcontrib>Fryer, Christy</creatorcontrib><creatorcontrib>Chen, Tracy</creatorcontrib><creatorcontrib>Twomey, Ariel Sterling</creatorcontrib><creatorcontrib>Ding, Jian</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Savage, Nik</au><au>Adair, Chris</au><au>Larraufie, Marie-Helene</au><au>Nakajima, Katsumasa</au><au>Isome, Yuko</au><au>Fryer, Christy</au><au>Chen, Tracy</au><au>Twomey, Ariel Sterling</au><au>Ding, Jian</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS</title><date>2024-03-15</date><risdate>2024</risdate><abstract>The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1 C3 dependent KARS inhibitor.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | hrv ; eng |
| recordid | cdi_epo_espacenet_HRP20231734TT1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T08%3A05%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Savage,%20Nik&rft.date=2024-03-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EHRP20231734TT1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |