TABLET FORMULATIONS OF NERATINIB MALEATE

TABLET FORMULATIONS OF NERATINIB MALEATE

The invention provides a high strength neratinib tablet and a method of its manufacturing comprising spraying intragranular components of a granulation comprising neratinib maleate, fillers, disintegrants and glidants, with a surface modifying agent and combining them with extragranular components c...

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Hauptverfasser: Ashraf, Muhammad, Nagi, Arwinder Singh, Ghosh, Krishnendu, Goolcharran, Chimanlall, Mahmud, Mainuddin
Format: Patent
Sprache:hrv ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Ashraf, Muhammad
Nagi, Arwinder Singh
Ghosh, Krishnendu
Goolcharran, Chimanlall
Mahmud, Mainuddin
description The invention provides a high strength neratinib tablet and a method of its manufacturing comprising spraying intragranular components of a granulation comprising neratinib maleate, fillers, disintegrants and glidants, with a surface modifying agent and combining them with extragranular components comprising fillers, disintegrants and lubricants.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TABLET FORMULATIONS OF NERATINIB MALEATE
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