PHARMACEUTICAL FORMULATIONS

This invention relates to pharmaceutical formulations comprising 1-(2-thien-2′-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2′-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl)...

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Hauptverfasser: Dutt, Chaitanya, Deshpande, Shailesh, Zambad, Shital Kumar, Gupta, Ramesh Chandra, Latad, Sachin, Chaudhari, Anita, Kesarwani, Amit, Abraham, Jaya, Mathur, Anoop, Patel, Manish, Kotecha, Jignesh, Mishra, Vivek
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creator Dutt, Chaitanya
Deshpande, Shailesh
Zambad, Shital Kumar
Gupta, Ramesh Chandra
Latad, Sachin
Chaudhari, Anita
Kesarwani, Amit
Abraham, Jaya
Mathur, Anoop
Patel, Manish
Kotecha, Jignesh
Mishra, Vivek
description This invention relates to pharmaceutical formulations comprising 1-(2-thien-2′-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2′-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl) pyridinium chloride. The formulations are suitable for oral administration and also comprise a permeability enhancer or a suitable base or a mixture thereof. The formulations of this invention are for treating diseases associated with advanced glycation end products.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHARMACEUTICAL FORMULATIONS
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