PROCESS FOR THE PREPARATION OF AN INTERMEDIATE POWDER FORMULATION AND A FINAL SOLID DOSAGE FORM UNDER USAGE OF A SPRAY CONGEALING STEP
Process for preparing a powder comprising the steps of providing at least one first component in liquid form at ambient temperature, providing at least one second component having a melting point or melting range in the range from above ambient temperature to below the degradation temperature of sai...
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| creator | Mertens, Roel Jos M Voorspoels, Jody Firmin Marceline Faure, Anne Kiekens, Filip Rene Irene |
| description | Process for preparing a powder comprising the steps of providing at least one first component in liquid form at ambient temperature, providing at least one second component having a melting point or melting range in the range from above ambient temperature to below the degradation temperature of said first component, forming a homogenous liquid mixture comprising the at least one first component and the at least one second component by stirring and heating the mixture to or keeping the mixture at a temperature in the range from above the melting point or melting range of the second component and below the degradation temperature of the first component, transferring the liquid mixture to at least one spray congealing unit, spray congealing the mixture, and isolating the powder obtained upon spray congealing. |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | PROCESS FOR THE PREPARATION OF AN INTERMEDIATE POWDER FORMULATION AND A FINAL SOLID DOSAGE FORM UNDER USAGE OF A SPRAY CONGEALING STEP |
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