GLUCAGON RECEPTOR MODULATOR

or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions th...

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Hauptverfasser:	Didiuk, Mary Theresa, Pfefferkorn, Jeffrey Allen, Tu, Meihua Mike, Guzman-Perez, Angel, Filipski, Kevin James, Lee, Esther Cheng Yin, Stevens, Benjamin Dawson, Aspnes, Gary Erik
Format:	Patent
Sprache:	hrv ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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creator	Didiuk, Mary Theresa Pfefferkorn, Jeffrey Allen Tu, Meihua Mike Guzman-Perez, Angel Filipski, Kevin James Lee, Esther Cheng Yin Stevens, Benjamin Dawson Aspnes, Gary Erik
description	or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
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Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.</description><language>hrv ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161104&DB=EPODOC&CC=HR&NR=P20161177T1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161104&DB=EPODOC&CC=HR&NR=P20161177T1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Didiuk, Mary Theresa</creatorcontrib><creatorcontrib>Pfefferkorn, Jeffrey Allen</creatorcontrib><creatorcontrib>Tu, Meihua Mike</creatorcontrib><creatorcontrib>Guzman-Perez, Angel</creatorcontrib><creatorcontrib>Filipski, Kevin James</creatorcontrib><creatorcontrib>Lee, Esther Cheng Yin</creatorcontrib><creatorcontrib>Stevens, Benjamin Dawson</creatorcontrib><creatorcontrib>Aspnes, Gary Erik</creatorcontrib><title>GLUCAGON RECEPTOR MODULATOR</title><description>or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. 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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
title	GLUCAGON RECEPTOR MODULATOR
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