SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS

This invention is directed to oxoazaheterocyclyl compounds which inhibit Factor Xa, to oxoazaheterocyclyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly i...

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Hauptverfasser: BARBARA A. HANNEY, CHRISTOPHER J. BURNS, WAN F. LAU, WILLIAM R. EWING, JOHN Z. JIANG, ALFRED P. SPADA, RODERICK S. DAVIS, YONG MI CHOI-SLEDESKI, MICHAEL R. MYERS, MICHAEL R. BECKER, WEI HE, STEPHEN M. CONDON, AIWEN LI, HEINZ W. PAULS, GREGORY B. POLI
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creator BARBARA A. HANNEY
CHRISTOPHER J. BURNS
WAN F. LAU
WILLIAM R. EWING
JOHN Z. JIANG
ALFRED P. SPADA
RODERICK S. DAVIS
YONG MI CHOI-SLEDESKI
MICHAEL R. MYERS
MICHAEL R. BECKER
WEI HE
STEPHEN M. CONDON
AIWEN LI
HEINZ W. PAULS
GREGORY B. POLI
description This invention is directed to oxoazaheterocyclyl compounds which inhibit Factor Xa, to oxoazaheterocyclyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS
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